1-(4-Fluorophenyl)cyclopentanecarboxylic acid → HCID 21957186, compound

Participants

Reaction Steps

Example 121 was prepared from 1-(4-fluorophenyl)cyclopentanecarboxylic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}cyclopropanecarboxamide according to the procedures described in Scheme 10: 1H NMR (400 MHz, CDCl3) δ 7.94–7.72 (br, 1H), 7.48–6.84 (m, 7H), 6.75 (d, 1H, J=7.2 Hz), 6.68–6.55 (br, 1H), 3.25–3.05 (m, 4H), 2.58–2.39 (m, 3H), 2.33–2.15 (m, 2H), 2.00–1.48 (m, 15H), 1.13–1.01 (m, 2H), 0.93–0.73 (m, 2H); ESMS m/e: 492.3 (M+H)+.

Provenance & Evidence