HCID 87828374, compound → HCID 10296304, compound

Participants

Reaction Steps

Methyl[3,5-dichloro-4-(4-acetamido-3-bromophenoxy)phenyl] acetate (100 mg) was coupled with n-tributylphenyltin (140 mg, 0.38 mmol), using the same procedure as described in Example 3(a). This gave 70 mg (70%) of methyl(3,5-dichloro-4-[4-acetamido-3-phenylphenoxy]phenyl) acetate. A part of the obtained ester (50 mg) was hydrolysed using the method described in Example 1(i), to give 45 mg (95%) of 3,5-dichloro-4-(4-acetamido-3-phenylphenoxy)phenylacetic acid, m/z 430.

Provenance & Evidence