Glycine, N-methyl-, hydrochloride (1:1) → HCID 10208081, compound

Participants

Reaction Steps

3,5-Dichloro-4-(3-bromo-4-isobutyramidophenoxy)phenylacetic acid (56 mg) was coupled with methyl glycine hydrochloride (31 mg) using the method described in Example 9. This gave methyl N-[3,5-dichloro-4-(3-bromo-4-isobutyramidophenoxy)phenylacetyl]-glycine, which was hydrolyzed using the method described in Example 1(i) and purified as in Example 9, to give 14 mg (22%) of N-[3,5-dichloro-4-(3-bromo-4-isobutyramidophenoxy)phenylacetyl]glycine, m/z 518.

Provenance & Evidence