Ethyl Acetate → HCID 86592334, compound

Participants

Reaction Steps

A mixture of ethyl(3,5-dichloro-4-[4-nitrophenoxy]phenyl) cinnamate (0.65 g), tindichloride dihydrate (1.0 g), ethylacetate (25 mL) and ethanol (25 mL) was heated at reflux for one hour. The reaction mixture was concentrated and the residue partioned beetween diethyl ether and sodium hydroxide (1 N). After purification on column (silica gel, ethyl acetate/petrolium ether, 3:7), 0.52 g of ethyl(3,5-dichloro-4-[4-aminophenoxy]phenyl) cinnamate was obtained.

Provenance & Evidence