Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 18448750 | HCID 18448750 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18448749 | HCID 18448749 | 52.4% |
Reaction Steps
Sodium methylate (2.2 g) was added to a solution of 3,5-dibromo-4-(4-nitrophenoxy)fluorobenzene (10 g) and dimethylformamide (25 mL). The reaction mixture was heated at 100° C. for 15 minutes. After cooling down to room temperature, concentration and purification on column (silica gel, ethyl acetate/petrolium ether, 1:9), 5.4 g of 3,5-dibromo-4-(4-nitrophenoxy)anisole was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07199265B2 |
|---|
| Source dataset | uspto-grants-2007_04 |
|---|
| ORD ID | ord-289924d7c3824c9a9a8b49e1d9137819 |
|---|
| Source note | uspto-grants-2007_04 |
|---|
