HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 1-Hydroxy-4-(beta-methylsulfonylethoxy)-N-n-hexadecyl-2-naphthamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 2-Naphthalenecarboxamide, N-hexadecyl-1,4-dihydroxy- | HCID 3089134 | — |
| Reactant | Methanesulfonylethanol | HCID 21979976 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Hydroxy-4-(beta-methylsulfonylethoxy)-N-n-hexadecyl-2-naphthamide | HCID 13643661 | — |
Reaction Steps
10 g (0.023 mol) of 1,4-dihydroxy-N-n-hexadecyl-2-naphthamide, 5.7 g (0.046 mol) of methylsulfonylethanol and 4.4 g (0.023 mol) of p-toluenesulfonic acid were added to 50 ml of dehydrated toluene. The mixture was refluxed with heating for 5 hours and the water produced was removed. Toluene was removed under reduced pressure. 100 ml of methanol was added to the mixture. The crystals thus deposited were collected by filtration to obtain 10.8 g (88%) of Coupler (2). Melting Point: 107° to 109° C. (recrystallized from methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04254212 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-0c77bb0b012e42618ef5473bf0aec8cb |
| Source note | uspto-grants-1981_03 |