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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269646Generated: October 30, 2026

(4-Methoxyphenyl)boronic acid → 4-Chloro-6-(4-methoxyphenyl)-5-methylpyrimidine

https://huagongshe.com/reaction/1269646

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Methoxyphenyl)boronic acidHCID 201262—
Reactant4,6-Dichloro-5-methylpyrimidineHCID 818860—
Reactant4-chloro-5-methyl-6-[4-(trifluoromethyl)phenyl]PyrimidineHCID 18448403—
Product4-Chloro-6-(4-methoxyphenyl)-5-methylpyrimidineHCID 18448405—

Reaction Steps

Prepared from 4-methoxyphenylboronic acid (0.93 g, 6.13 mmol) and 4,6-dichloro-5-methylpyrimidine using the procedure described for Intermediate 62.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199239B2
Source datasetuspto-grants-2007_04
ORD IDord-be6a40a0203049d18764ee25a3b2ba23
Source noteuspto-grants-2007_04