HRID1269650

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18448402

未命名化合物

HCID58622846

未命名化合物

结构：CCCCN(Cc1ccc(OCC(=O)OCC)c(C)c1)c1ncnc(-c2ccc(OC)cc2)c1C

HCID58622872

未命名化合物

PRODUCTS

生成物

结构：CCCCN(Cc1ccc(OCC(=O)OCC)c(C)c1)c1ncnc(-c2ccc(C)cc2)c1C

HCID58622847

未命名化合物

PROCEDURE

实验过程

Prepared from 4-chloro-5-methyl-6-(4-methylphenyl)pyrimidine and ethyl {4-[(butylamino)methyl]-2-methylphenoxy}acetate using the procedure of Intermediate 67.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-40effd639b744a36a1313a0f97941c15
来源数据集: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07199239B2
来源说明: uspto-grants-2007_04

反应 SMILES

Cl[C:2]1[C:7]([CH3:8])=[C:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH2:16]([NH:20][CH2:21][C:22]1[CH:34]=[CH:33][C:25]([O:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[C:24]([CH3:35])[CH:23]=1)[CH2:17][CH2:18][CH3:19].C(N(CC1C=CC(OCC(OCC)=O)=C(C)C=1)C1C(C)=C(C2C=CC(OC)=CC=2)N=CN=1)CCC>>[CH2:16]([N:20]([CH2:21][C:22]1[CH:34]=[CH:33][C:25]([O:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[C:24]([CH3:35])[CH:23]=1)[C:2]1[C:7]([CH3:8])=[C:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)[N:5]=[CH:4][N:3]=1)[CH2:17][CH2:18][CH3:19]