4-(Trifluoromethyl)phenylboronic acid → HCID 18448272, compound

HRID 1269698Notes

Reaction equation

HRID 1269698 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1.Br[C:15]1[C:16]([CH3:40])=[C:17]([N:21]([CH2:25][C:26]2[CH:38]=[CH:37][C:29]([O:30][CH2:31][C:32]([O:34]CC)=[O:33])=[C:28]([CH3:39])[CH:27]=2)[CH2:22][CH2:23][CH3:24])[CH:18]=[CH:19][CH:20]=1>>[CH3:39][C:28]1[CH:27]=[C:26]([CH2:25][N:21]([C:17]2[C:16]([CH3:40])=[C:15]([C:6]3[CH:7]=[CH:8][C:3]([C:2]([F:13])([F:12])[F:1])=[CH:4][CH:5]=3)[CH:20]=[CH:19][CH:18]=2)[CH2:22][CH2:23][CH3:24])[CH:38]=[CH:37][C:29]=1[O:30][CH2:31][C:32]([OH:34])=[O:33]

Participants

3

Reactant 2

HCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 58622881HCID 58622881, compound

Product 1

HCID 18448272HCID 18448272, compound

Procedure

Prepared from 4-(trifluoromethyl)phenylboronic acid and ethyl (4-{[(3-bromo-2-methylphenyl)(propyl)amino]methyl}-2-methylphenoxy)acetate using the procedure described for Example 25 (Method A).

Sources & evidence

ORD record
ord-0adf68df2af04a5c90214121cc8193e0
Source dataset
uspto-grants-2007_04
Patent number
US07199239B2

Reaction notes

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