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5-{[4-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]oxy}-1H-indazole → 5-(Pyrrolidin-3-yloxy)-1H-indazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-{[4-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]oxy}-1H-indazole | HCID 18447207 | — |
| 反応物 | 4-(1H-indazol-5-yloxy)cyclohexanol | HCID 22933369 | — |
| 生成物 | 5-(Pyrrolidin-3-yloxy)-1H-indazole | HCID 22933398 | — |
反応手順
The following compound of Example 379 was synthesized by carrying out reactions according to the methods described in Example 372, (b) and Example 377 except for using the tert-butyl 4-hydroxyazepane-1-carboxylate obtained in Example 322, (c), as a reagent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07199147B2 |
| 出典データセット | uspto-grants-2007_04 |
| ORD ID | ord-d951db50d9cf45e898ab537e61d46b0e |
| 出典メモ | uspto-grants-2007_04 |