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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269812Generated: October 25, 2026

5-{[4-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]oxy}-1H-indazole → trans-3-(1H-indazol-5-yloxy)cyclohexanamine

https://huagongshe.com/reaction/1269812

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-{[4-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]oxy}-1H-indazoleHCID 18447207—
Reactant4-(1H-indazol-5-yloxy)cyclohexanolHCID 22933369—
Producttrans-3-(1H-indazol-5-yloxy)cyclohexanamineHCID 69435923—

Reaction Steps

The following compound of Example 384 was synthesized by carrying out reactions according to the methods described in Example 372, (b) and Example 381, except for using the cis-2-(4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione obtained in Example 323, (c), as a starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199147B2
Source datasetuspto-grants-2007_04
ORD IDord-6d9054ca31164e649f7f4daea8bb63e7
Source noteuspto-grants-2007_04