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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269851Generated: November 1, 2026

Methyl 2-(3-methyl-4-nitrophenoxy)benzoate → Methyl 2-(4-amino-3-methylphenoxy)benzoate

https://huagongshe.com/reaction/1269851

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-methyl-4-nitrophenoxy)benzoateHCID 22933655—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
ProductMethyl 2-(4-amino-3-methylphenoxy)benzoateHCID 2293336092%

Reaction Steps

Under a hydrogen atmosphere at atmospheric pressure, a solution of methyl 2-(3-methyl-4-nitrophenoxy)-benzoate (1.85 g, 6.44 mmol) in a mixture of ethyl acetate (15 ml) and methanol (8 ml) was stirred at room temperature for 5 hours. The solution was filtered and the filtrate was concentrated to obtain methyl 2-(4-amino-3-methylphenoxy)-benzoate (1.52 g, 92%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199147B2
Source datasetuspto-grants-2007_04
ORD IDord-90461e4afca441f7b091438032815a4c
Source noteuspto-grants-2007_04