HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(3-methyl-4-nitrophenoxy)benzoate → Methyl 2-(4-amino-3-methylphenoxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(3-methyl-4-nitrophenoxy)benzoate | HCID 22933655 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 2-(4-amino-3-methylphenoxy)benzoate | HCID 22933360 | 92% |
Reaction Steps
Under a hydrogen atmosphere at atmospheric pressure, a solution of methyl 2-(3-methyl-4-nitrophenoxy)-benzoate (1.85 g, 6.44 mmol) in a mixture of ethyl acetate (15 ml) and methanol (8 ml) was stirred at room temperature for 5 hours. The solution was filtered and the filtrate was concentrated to obtain methyl 2-(4-amino-3-methylphenoxy)-benzoate (1.52 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199147B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-90461e4afca441f7b091438032815a4c |
| Source note | uspto-grants-2007_04 |