HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 6-Bromomethyl-nicotinic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 6-methylnicotinate | HCID 231548 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 6-Bromomethyl-nicotinic acid methyl ester | HCID 12752237 | — |
Reaction Steps
To a solution of methyl 6-methylnicotinate (50 g, 331 mmol) in carbon tetrachloride (625 mL), was added N-bromosuccinimide (59 g, 331 mmol). Further 1.0 g of benzoyl peroxide was added, the mixture was reacted at a temperature from 40 to 50° C. for 24 hours with irradiation of light from a projector.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07202093B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-780eb17e0351482aadf4b04c0a9730fc |
| Source note | uspto-grants-2007_04 |