HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270044Generated: October 30, 2026
Acetic Anhydride → (4-Nitropyridin-2-yl)methyl acetate
https://huagongshe.com/reaction/1270044
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Pyridine, 2-methyl-4-nitro-, 1-oxide | HCID 95291 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (4-Nitropyridin-2-yl)methyl acetate | HCID 14761430 | — |
Reaction Steps
200 mL of acetic anhydride was heated to 100° C., followed by gradual addition of 2-methyl-4-nitropyridine N-oxide (25.0 g, 162 mmol). After the addition, the mixture was gradually heated, and was kept at 130° C. for 20 minutes. Then, the reaction mixture was cooled to 80° C., followed by dropwise addition of 200 mL of ethanol to stop the reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07202093B2 |
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| Source dataset | uspto-grants-2007_04 |
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| ORD ID | ord-0458662f3c914a128d06582f9b9f9852 |
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| Source note | uspto-grants-2007_04 |
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