Putrescine → HCID 18448974, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 7-chloro-1-methyl-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (1.0 g, prepared according to H. Agui and T. Nakagome, J. Heterocycl. Chem., (1979), 16(7), 1353–60) in 1-methyl-2-pyrrolidinone (10 mL), was added 1,4-diaminobutane (1.84 g). The mixture was heated at 130° C. for 17 hours. The reaction mixture was cooled and poured into DCM (20 mL). The precipitate obtained was dispersed in MeOH and filtered to give the title compound (860 mg).

Provenance & Evidence