Ethylenediamine → HCID 18448979, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 7-chloro-1-methyl-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (1.5 g, prepared according to H. Agui and T. Nakagome, J. Heterocycl. Chem., (1979), 16(7), 1353–60) in 1-methyl-2-pyrrolidinone (15 mL), was added ethylenediamine (1.9 g). The mixture was heated at 130° C. for 24 hours. The reaction mixture was cooled and poured into DCM (20 mL). The precipitate obtained was dispersed in MeOH, filtered giving the title compound (500 mg).

Provenance & Evidence