7-Methoxy-2-naphthol → 1-[(2,3-Dimethoxyphenyl)-morpholin-4-yl-methyl]-7-methoxy-naphthalen-2-ol

HRID 1270116Notes

Reaction equation

HRID 1270116 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9]([OH:13])=[CH:10]2)=[CH:5][CH:4]=1.[Cl-].[CH3:15][O:16][C:17]1[C:29]([O:30][CH3:31])=[CH:28][CH:27]=[CH:26][C:18]=1[CH:19]=[N+:20]1[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1>>[CH3:15][O:16][C:17]1[C:29]([O:30][CH3:31])=[CH:28][CH:27]=[CH:26][C:18]=1[CH:19]([N:20]1[CH2:21][CH2:22][O:23][CH2:24][CH2:25]1)[C:10]1[C:11]2[C:6](=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[CH:12]=2)[CH:7]=[CH:8][C:9]=1[OH:13]

Participants

3

Reactant 2

HCID 8531737-Methoxy-2-naphtholHCID 221747594-(2,3-Dimethoxy-benzylidene)-morpholin-4-ium chloride

Product 1

HCID 235008591-[(2,3-Dimethoxyphenyl)-morpholin-4-yl-methyl]-7-methoxy-naphthalen-2-ol

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 7-methoxy-2-naphthol and 4-(2,3-dimethoxy-benzylidene)-morpholin-4-ium chloride, which had been prepared in accordance with example 21.

Workup

  1. customhad been prepared in accordance with example 21

Sources & evidence

ORD record
ord-f1e51c843d194530ad89b9dbb8e1620f
Source dataset
uspto-grants-2007_04
Patent number
US07202242B2

Reaction notes

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