HCID 69421658, compound → HCID 69098969, compound

Participants

Reaction Steps

A solution of [3-(4-Chloro-2-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester (1.78 g) was hydrogenated in ethanol (50 ml) in presence of Platinum oxide (178 mg) for 2 hours. The mixture was filtrated over a pad of celite and concentrated under vacuum. The crude reaction was purified by flash chromatography to afford [3-(2-Amino-4-chloro-phenoxy)-propyl]-carbamic acid tert-butyl ester (1.39 g, yield=86%) as a viscous oil which solidified slowly:

Provenance & Evidence