反应详情

To a mixture of 40 mg of 8-bromo-4-isopropylamino-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one and 40 mg of 10% Pd/C in a 1:1 mixture of MeOH/EtOH was added 81 mg of cyclohexene. This mixture was heated at reflux for 3.5 hrs. and then stirred at room temperature for 18 hrs. The reaction mixture was diluted with chloroform, filtered through a pad of diatomaceous earth, and concentrated. The residue was triturated with IPE to provide an orange solid. MS (M+H)+=244.0.

1. temperatureThis mixture was heated
2. temperatureat reflux for 3.5 hrs
3. filtrationfiltered through a pad of diatomaceous earth
4. concentrationconcentrated
5. customThe residue was triturated with IPE
6. customto provide an orange solid