HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270157Generated: November 1, 2026
Diethyl Oxalate → Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate
https://huagongshe.com/reaction/1270157
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | 3,5-Diamino-2-methylbenzoic acid | HCID 135524 | — |
| Product | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate | HCID 23847563 | — |
Reaction Steps
A mixture of methyl-3,4-diaminobenzoate (4.5 g) in diethyloxalate (50 mL) was heated at reflux for three hrs. After cooling to 23° C., the solid was isolated by filtration, affording 2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid methyl ester as a light yellow solid. MS (M−H)−=219.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07202245B2 |
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| Source dataset | uspto-grants-2007_04 |
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| ORD ID | ord-cec1be3dd0604c3991de92514d48098e |
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| Source note | uspto-grants-2007_04 |
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