Isopropylamine → HCID 69415181, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-chloro-1-methoxy-[1,2,4]triazolo[4,3-a]quinoxaline-7-carboxylic acid methyl ester (80 mg), isopropylamine (24 mg) and sodium bicarbonate (45 mg) in DMF (2 mL) was stirred at 23° C. for 17 hrs. The mixture was then partitioned between water and EtOAc. The organic layer was washed with brine, dried over sodium sulfate, and concentrated. Trituration with EtOAc/hexanes afforded 4-isopropylamino-1-methoxy-[1,2,4]triazolo[4,3-a]quinoxaline-7-carboxylic acid methyl ester as a light yellow solid. MS (M+H)+=316.3.

Provenance & Evidence