4-Pyridineethanamine → HCID 69415327, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-chloro-1-methoxy-[1,2,4]triazolo[4,3-a]quinoxaline-7-carboxylic acid methyl ester (80 mg), 2-(4-pyridyl)ethylamine (50 mg), and sodium bicarbonate (45 mg) in DMF (2 mL) was stirred at 50° C. for 15 hrs. The mixture was cooled to 23° C., and then diluted with water and EtOAc. A precipitate formed which was isolated by filtration to afford 1-methoxy-4-(2-pyridin-4-ylethylamino)-[1,2,4]triazolo[4,3-a]quinoxaline-7-carboxylic acid methyl ester. MS (M+H)+=379.3.

Provenance & Evidence