1,2-Dichloroethane → HCID 86594421, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-isopropylamino-1-oxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxaline-7-carboxylic acid (130 mg), N,O-dimethylhydroxylamine hydrochloride (39 mg), HOBT (54 mg), and EDC (77 mg) in DMF (4.0 mL) was stirred at 23° C. for 20 hrs. The solution was then diluted with EtOAc and washed sequentially with saturated aqueous sodium bicarbonate and saturated aqueous sodium chloride solutions. The organic layer was dried over sodium sulfate, filtered, and the filtrate concentrated to afford the title compound as a light yellow solid. MS (M+H)+=331.6.

Provenance & Evidence