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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270312Generated: November 2, 2026

5,7-dimethyl-2-(4-nitrophenyl)-N-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-4-amine → N-[2-(4-Aminophenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4-yl]-N-(3,4,5-trimethoxyphenyl)amine

https://huagongshe.com/reaction/1270312

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,7-dimethyl-2-(4-nitrophenyl)-N-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-4-amineHCID 22329643—
CatalystPalladiumHCID 23938—
ProductN-[2-(4-Aminophenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4-yl]-N-(3,4,5-trimethoxyphenyl)amineHCID 11742877—

Reaction Steps

620 mg (1.38 mmol) of 5,7-dimethyl-2-(4-nitrophenyl)-N-(3,4,5-trimethoxyphenyl)-imidazo[5,1-f][1,2,4]triazin-4-amine from example 17A are hydrogenated in the presence of 200 mg of palladium on carbon (10% strength) analogously to example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07202243B2
Source datasetuspto-grants-2007_04
ORD IDord-3207a788f4e34f9e88c7c5c07c419c70
Source noteuspto-grants-2007_04