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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270393Generated: October 26, 2026

2,4-Dibromo-1,3-thiazole → tert-Butyl [3-(4-bromo-1,3-thiazol-2-yl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetate

https://huagongshe.com/reaction/1270393

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dibromo-1,3-thiazoleHCID 2763297—
ReactantTert-butyl (2-oxo-2,3-dihydrobenzimidazol-1-yl)acetateHCID 20814117—
Producttert-Butyl [3-(4-bromo-1,3-thiazol-2-yl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetateHCID 86607786—

Reaction Steps

Essentially following the procedures described for Intermediate 4, but using 2,4-dibromothiazole in place of 2-bromopyridine, the title compound was prepared. MS: m/z=412 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07202251B2
Source datasetuspto-grants-2007_04
ORD IDord-2a9da5bcf3814d98aafd4580e409c18c
Source noteuspto-grants-2007_04