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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270552Generated: October 27, 2026

1-Bromo-2-Chloroethane → 1-(2-Chloroethyl)4-(trifluoromethyl)piperidin-4-ol

https://huagongshe.com/reaction/1270552

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-ChloroethaneHCID 7849—
Reactant4-(Trifluoromethyl)-4-piperidinolHCID 17951321—
Product1-(2-Chloroethyl)4-(trifluoromethyl)piperidin-4-olHCID 18449829—

Reaction Steps

A solution of 4-(trifluoromethyl)piperidin-4-ol and 1-bromo-2-chloroethane are reacted using the procedure for Example OO to afford 1-(2-chloroethyl)-4-(trifluoromethyl)piperidin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07202257B2
Source datasetuspto-grants-2007_04
ORD IDord-833075b86cdc4fff880a052e8a04f09e
Source noteuspto-grants-2007_04