N-[2-Hydroxy-3-(1-naphthoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride → N-[2-hydroxy-3-(3,4-dimethoxyphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride
Reaction equation
[ClH:1].[O:2](CCCNC(C)(C)CC1C=CC(OC)=CC=1)[C:3]1C=CC=CC=1.Cl.OC(COC1C=CC(C(C)(C)C)=CC=1)CNC(C)(C)CC1C=CC(OC)=CC=1.Cl.O[C@H](COC1C=CC(C(C)(C)C)=CC=1)CNC(C)(C)CC1C=CC(OC)=CC=1.Cl.OC(COC1C2C(=CC=CC=2)C=CC=1)CNC(C)(C)CC1C=CC(OC)=CC=1.Cl.[OH:113][CH:114]([CH2:129][O:130][C:131]1[CH:136]=[CH:135][C:134]([O:137][CH3:138])=[CH:133][CH:132]=1)[CH2:115][NH:116][C:117]([CH3:128])([CH3:127])[CH2:118][C:119]1[CH:124]=[CH:123][C:122]([O:125][CH3:126])=[CH:121][CH:120]=1>>[ClH:1].[OH:113][CH:114]([CH2:129][O:130][C:131]1[CH:136]=[CH:135][C:134]([O:137][CH3:138])=[C:133]([O:2][CH3:3])[CH:132]=1)[CH2:115][NH:116][C:117]([CH3:128])([CH3:127])[CH2:118][C:119]1[CH:120]=[CH:121][C:122]([O:125][CH3:126])=[CH:123][CH:124]=1Participants
6
Reactant 5
Product 1
Procedure
GC/EI-MS, m/z (rel. int.) 390 (M+, 0.0), 269 (17), 268 (100), 163 (6), 153 (5), 121 (21), 114 (17), 77 (5), 71 (19), 70 (17), 58 (7).
Sources & evidence
- ORD record
- ord-d9efb9cf69144c05a4f75f979adc5bee
- Source dataset
- uspto-grants-2007_04
- Patent number
- US07202261B2
Reaction notes
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