N-[2-Hydroxy-3-(4-t-butylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride → N-[2-hydroxy-3-(3-iso-propylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

HRID 1270654Notes

Reaction equation

HRID 1270654 reaction equation
[ClH:1].[OH:2][CH:3]([CH2:18][O:19]C1C=CC(C(C)(C)C)=CC=1)[CH2:4][NH:5][C:6]([CH3:17])([CH3:16])[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1.Cl.O[C@H](CO[C:49]1[CH:54]=[CH:53][C:52]([C:55](C)([CH3:57])[CH3:56])=[CH:51][CH:50]=1)CNC(C)(C)CC1C=CC(OC)=CC=1>>[ClH:1].[OH:2][CH:3]([CH2:18][O:19][C:50]1[CH:49]=[CH:54][CH:53]=[C:52]([CH:55]([CH3:57])[CH3:56])[CH:51]=1)[CH2:4][NH:5][C:6]([CH3:17])([CH3:16])[CH2:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH3:15])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 22640914N-[2-Hydroxy-3-(4-t-butylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine HydrochlorideHCID 69471426(S)-N-[2-Hydroxy-3-(4-t-butylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

Product 1

HCID 22640890N-[2-hydroxy-3-(3-iso-propylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

Procedure

GC/EI-MS, m/z (rel. int.) 356 (M−15, 0.1), 251 (18), 250 (100), 163 (6), 121 (21), 117 (5), 114 (10), 91 (9).

Sources & evidence

ORD record
ord-d1cdadec242e4042bc45535b357515e1
Source dataset
uspto-grants-2007_04
Patent number
US07202261B2

Reaction notes

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