HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylpyrazole → Dimethylphenylpyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylpyrazole | HCID 6210 | — |
| Reactant | Iodobenzene | HCID 11575 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Dimethylphenylpyrazole | HCID 70800 | — |
Reaction Steps
Operating protocol A (110° C., 54 hours) was followed using 117 mg of Chxn-Py-Al (0.4 mmoles), 336 μl of iodobenzene (3 mmoles), 192 mg of 3,5-dimethylpyrazole (2 mmoles) and 1.2 ml of DMF. The degree of transformation and selectivity for 5-dimethyl-1-phenyl-1H-pyrazole were 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07202367B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-36de2c5987094dc7b6bdaef0af662604 |
| Source note | uspto-grants-2007_04 |