1-Methyl-1H-indole-2-carbonyl chloride → N-[4-(4-amino-7-{[3-(4-methylpiperazin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-1H-indole-2-carbonyl chloride	HCID 12303314	—
Reactant	N-[4-amino-3-(4-amino-3-methoxyphenyl)thieno[3,2-c]pyridin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide	HCID 18451407	—
Product	N-[4-(4-amino-7-{[3-(4-methylpiperazin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide	HCID 18451129	—

Reaction Steps

The title compound was prepared using 1-methyl-1H-indole-2-carbonyl chloride, N-[4-amino-3-(4-amino-3-methoxyphenyl)thieno[3,2-c]pyridin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide, and the procedure described in General Procedure F. m/z (M+H)+598.4.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07202363B2
Source dataset	uspto-grants-2007_04
ORD ID	ord-942b8b64680a4fe686e9c2a53a6accca
Source note	uspto-grants-2007_04