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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270958Generated: November 3, 2026

1-Methyl-1H-indole-2-carbonyl chloride → N-[4-(4-amino-7-{[3-(diethylamino)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide

https://huagongshe.com/reaction/1270958

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-indole-2-carbonyl chlorideHCID 12303314—
ReactantN-[4-Amino-3-(4-amino-3-methoxyphenyl)thieno[3,2-c]pyridin-7-yl]-3-diethylaminopropionamideHCID 18451408—
ProductN-[4-(4-amino-7-{[3-(diethylamino)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamideHCID 18451165—

Reaction Steps

The title compound was prepared using 1-methyl-1H-indole-2-carbonyl chloride, N-[4-Amino-3-(4-amino-3-methoxyphenyl)thieno[3,2-c]pyridin-7-yl]-3-diethylaminopropionamide, and the procedure described in General Procedure F. m/z (M+H)+571.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07202363B2
Source datasetuspto-grants-2007_04
ORD IDord-53829e9c2a24403fa284ee43897d5d7d
Source noteuspto-grants-2007_04