HCID 18452815, compound → HCID 10292096, compound

Participants

Reaction Steps

Prepared in a similar fashion as described for Example 413 using 3,5-dichloro-1-(1-ethylpropyl)-2(1H)-pyrazinone and 5-methoxy-7-methylindoline hydrochloride as the starting materials. mp 164–165° C.; 1H NMR (300 MHz, CDCl3): δ 6.67 (s, 1 H), 6.66 (s, 1 H), 6.59 (d, J=2.2 Hz, 1 H), 4.82–4.80 (m, 1 H), 4.39 (t, J=7.9 Hz, 2 H), 3.79 (s, 3 H), 3.05 (t, J=7.7 Hz, 2 H), 2.06 (s, 3 H), 1.84–1.73 (m, 2 H), 1.70–1.59 (m, 2 H), 0.89 (t, J=7.3 Hz, 6 H); HRMS (ESI) calcd for C19H25N3O2Cl (M+H)+: 362.1635; found m/z 362.1648.

Provenance & Evidence