Ethanol → HCID 70571949, compound

HRID 127118Notes

Reaction equation

HRID 127118 reaction equation
[Br:1][CH:2]([C:7](=O)C)[CH2:3][C:4]([OH:6])=[O:5].[NH2:10][C:11]([NH2:13])=[S:12].[CH2:14](O)C>>[BrH:1].[NH2:10][C:11]1[S:12][CH2:14][C:2]([CH2:3][C:4]([OH:6])=[O:5])([CH3:7])[N:13]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 2723790ThioureaHCID 129339473-Bromo-4-oxopentanoic acid

Product 1

HCID 70571949HCID 70571949, compound

Procedure

To a mixture of 3-bromo-4-oxovaleric acid (4.0 g.) in ethanol (50 ml.) was added powder of thiourea (1.6 g.) and the mixture was stirred for 3 hours at the room temperature, and then the precipitated crystals were collected by filtration and then dried to give 2-amino-4-methylthiazol-4-ylacetic acid hydrobromide (1.5 g.).

Workup

  1. filtrationthe precipitated crystals were collected by filtration
  2. customdried

Sources & evidence

ORD record
ord-7044301d793d4f6b99ddaddefcc720d2
Source dataset
uspto-grants-1981_03
Patent number
US04254260

Reaction notes

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