Benzyl 2-(3-hydroxyprop-1-en-1-yl)pyrrolidine-1-carboxylate → 3-(Pyrrolidin-2-yl)propan-1-ol

Participants

Reaction Conditions

Reaction Steps

0.73 g of (±)-3-(N-benzyloxycarbonylpyrrolidin-2-yl)-2-propen-1-ol was dissolved in 7 ml of ethanol and, after adding 200 mg of 5% palladium-carbon, the mixture was heated to 35° C. and hydrogenated at atmospheric pressure for 8 hours. A catalyst was removed by filtering the reaction solution and the filtrate was concentrated under reduced pressure to obtain 0.34 g of the desired compound as a pale yellow oily substance.

Provenance & Evidence