HCID 86592463, compound → HCID 86592462, compound

Participants

Reaction Steps

To a solution of 1.57 g of 2-[4-hydroxy-(Z)-2-buten-1-yloxy]acetic acid methyl ester in 157 ml of benzene, 7.90 g of celite and 4.87 g of pyridinium chlorochromate were added, followed by stirring at room temperature for 23 hours. The insoluble matter was removed by filtration and the solvent in the filtrate was evaporated under reduced pressure. After the was dissolved in ethyl acetate, the insoluble matter was removed by filtering trough celite to obtain 311 mg of the desired crude product as a brown oily substance.

Provenance & Evidence