5-Chloro-2,3-Diphenylpyrazine → HCID 22932020, compound

HRID 1271286Notes

Reaction equation

HRID 1271286 reaction equation
Cl[C:2]1[CH:7]=[N:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1.[CH3:20][NH:21][CH:22]1[C:30]2[C:25](=[C:26]([O:31][CH2:32][O:33][CH3:34])[CH:27]=[CH:28][CH:29]=2)[CH2:24][CH2:23]1.CNCCCCO>>[C:8]1([C:5]2[N:6]=[CH:7][C:2]([N:21]([CH:22]3[C:30]4[C:25](=[C:26]([O:31][CH2:32][O:33][CH3:34])[CH:27]=[CH:28][CH:29]=4)[CH2:24][CH2:23]3)[CH3:20])=[N:3][C:4]=2[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

4

Reactant 3

HCID 36544935-Chloro-2,3-DiphenylpyrazineHCID 98339374-(Methylamino)butan-1-olHCID 22931945HCID 22931945, compound

Product 1

HCID 22932020HCID 22932020, compound

Procedure

In the same manner as in the step 1 of Example 9, except that 2-chloro-5,6-diphenylpyrazine was used in place of 2-chloro-5,6-di-p-tolylpyrazine and 1-methylamino-4-(methoxymethoxy)indane was use in place of 4-(methylamino)-1-butanol, the desired compound was prepared as a pale yellow oily substance.

Sources & evidence

ORD record
ord-bbc7863ade7d4214b310b10fba609297
Source dataset
uspto-grants-2007_04
Patent number
US07205302B2

Reaction notes

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