5,6-Diphenyl-2-(ethylamino)pyrazine → 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-ethylamino]butyloxy}acetic Acid Tert-Butyl Ester
反応式
[C:1]1([C:7]2[N:8]=[CH:9][C:10]([NH:19][CH2:20][CH3:21])=[N:11][C:12]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:22]([O:26][C:27](=[O:35])[CH2:28][O:29][CH2:30][CH2:31][CH2:32][CH2:33]Br)([CH3:25])([CH3:24])[CH3:23]>>[C:22]([O:26][C:27](=[O:35])[CH2:28][O:29][CH2:30][CH2:31][CH2:32][CH2:33][N:19]([C:10]1[CH:9]=[N:8][C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:11]=1)[CH2:20][CH3:21])([CH3:25])([CH3:24])[CH3:23]参加物
3
実験手順
In the same manner as in Example 22, except that 5,6-diphenyl-2-(ethylamino)pyrazine was used in place of 5,6-diphenyl-2-(methylamino)pyrazine and 2-(4-bromobutyloxy)acetic acid tert-butyl ester was used in place of 2-(4-bromobutyloxy)acetic acid methyl ester, the desired compound was prepared as a pale yellow oily substance.
出典と根拠
- ORDレコード
- ord-9b165cbe2f9d4c3b9a570692c3327b7d
- 出典データセット
- uspto-grants-2007_04
- 特許番号
- US07205302B2
反応ノート
読み込み中…