2-Allylamino-5,6-diphenylpyrazine → 2-{4-[N-allyl-N-(5,6-diphenylpyrazin-2-yl)amino]butyloxy}acetic Acid Tert-Butyl Ester

HRID 1271290Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1271290
[CH2:1]([NH:4][C:5]1[CH:10]=[N:9][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[C:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:6]=1)[CH:2]=[CH2:3].[C:23]([O:27][C:28](=[O:36])[CH2:29][O:30][CH2:31][CH2:32][CH2:33][CH2:34]Br)([CH3:26])([CH3:25])[CH3:24]>>[C:23]([O:27][C:28](=[O:36])[CH2:29][O:30][CH2:31][CH2:32][CH2:33][CH2:34][N:4]([CH2:1][CH:2]=[CH2:3])[C:5]1[CH:10]=[N:9][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[C:7]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:6]=1)([CH3:26])([CH3:25])[CH3:24]

Komponenten

3

Edukt 2

HCID 229320162-Allylamino-5,6-diphenylpyrazineHCID 86592459Tert-butyl (4-bromobutyloxy)acetate

Produkt 1

HCID 693555542-{4-[N-allyl-N-(5,6-diphenylpyrazin-2-yl)amino]butyloxy}acetic Acid Tert-Butyl Ester

Versuchsvorschrift

In the same manner as in Example 22, except that 2-allylamino-5,6-diphenylpyrazine was used in place of 5,6-diphenyl-2-(methylamino)pyrazine and 2-(4-bromobutyloxy)acetic acid tert-butyl ester was used in place of 2-(4-bromobutyloxy)acetic acid methyl ester, the desired compound was prepared as a pale yellow oily substance.

Quellen und Nachweise

ORD-Eintrag
ord-619dae64f824460eb2806030624d88ca
Quelldatensatz
uspto-grants-2007_04
Patentnummer
US07205302B2

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