Sodium Hydroxide → HCID 44434439, compound

HRID 1271305Notes

Reaction equation

HRID 1271305 reaction equation
C([O:5][C:6](=[O:33])[CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]([C:15]1[CH:20]=[CH:19][C:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[C:17]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[N:16]=1)[CH3:14])(C)(C)C.C1(C2C=CC(N(CCCCOCC(O)=O)C)=NC=2C2C=CC=CC=2)C=CC=CC=1.[OH-].[Na+:64]>>[Na+:64].[C:21]1([C:18]2[CH:19]=[CH:20][C:15]([N:13]([CH2:12][CH2:11][CH2:10][CH2:9][O:8][CH2:7][C:6]([O-:33])=[O:5])[CH3:14])=[N:16][C:17]=2[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 18452628HCID 18452628, compoundHCID 69354729HCID 69354729, compound

Product 1

HCID 44434439HCID 44434439, compound

Procedure

After 2-{4-[N-(5,6-diphenylpyridin-2-yl)-N-methylamino]butyloxy}acetic acid tert-butyl ester was hydrolyzed in the same manner as in Example 42, the resulting 2-{4-[N-(5,6-diphenylpyridin-2-yl)-N-methylamino]butyloxy}acetic acid was treated with the same amount of 1N sodium hydroxide solution to obtain the desired compound as a pale brown amorphous.

Sources & evidence

ORD record
ord-d8d9651e6ed1474e8389bfa5d5fcf7ca
Source dataset
uspto-grants-2007_04
Patent number
US07205302B2

Reaction notes

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