HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl [(3R,7R)-3-amino-2-oxo-7-phenylazepan-1-yl]acetate → tert-Butyl [(3R,7R)-2-oxo-3-({[4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidin-1-yl]carbonyl}amino)-7-phenylazepan-1-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl [(3R,7R)-3-amino-2-oxo-7-phenylazepan-1-yl]acetate | HCID 14003455 | — |
| Reactant | 4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carbonyl chloride | HCID 18321108 | — |
| Product | tert-Butyl [(3R,7R)-2-oxo-3-({[4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidin-1-yl]carbonyl}amino)-7-phenylazepan-1-yl]acetate | HCID 11342179 | — |
Reaction Steps
The title compound was prepared with tert-butyl [(3R,7R)-3-amino-2-oxo-7-phenylazepan-1-yl]acetate and 4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carbonyl chloride using a similar procedure to Example 1. MS 576 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07205292B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-90409d934384473bae72d170c76a12d0 |
| Source note | uspto-grants-2007_04 |