HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carbonyl chloride → N-((3S,6R)-1-(cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carbonyl chloride | HCID 18321108 | — |
| Reactant | (3S,6R)-3-amino-1-(cyclopropylmethyl)-6-phenylazepan-2-one | HCID 68565986 | — |
| Product | N-((3S,6R)-1-(cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide | HCID 11352820 | — |
Reaction Steps
The title compound was prepared with (3S,6R)-3-amino-1-(cyclopropylmethyl)-6-phenylazepan-2-one and 4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carbonyl chloride using a similar procedure to Example 4. MS 516 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07205292B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-2e4e8d9e2d954ec3afbaaef66e84b533 |
| Source note | uspto-grants-2007_04 |