Diethyl Ether → HCID 10083116, compound

HRID 1271569Notes

Reaction equation

HRID 1271569 reaction equation
C(OCC)C.[Cl:6][C:7]1[CH:8]=[C:9]([C:13]#[C:14][C:15]2[C:20]([NH2:21])=[CH:19][CH:18]=[C:17]([CH3:22])[N:16]=2)[CH:10]=[CH:11][CH:12]=1>>[ClH:6].[Cl:6][C:7]1[CH:8]=[C:9]([C:13]#[C:14][C:15]2[C:20]([NH2:21])=[CH:19][CH:18]=[C:17]([CH3:22])[N:16]=2)[CH:10]=[CH:11][CH:12]=1.[Cl:6][C:7]1[CH:8]=[C:9]([C:13]#[C:14][C:15]2[C:20]([NH2:21])=[CH:19][CH:18]=[C:17]([CH3:22])[N:16]=2)[CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 2

HCID 3283Diethyl EtherHCID 10083116HCID 10083116, compound

Product 2

HCID 10083116HCID 10083116, compoundHCID 18454770HCID 18454770, compound

Procedure

The hydrochloride of (2-(3-chloro-phenylethynyl)-6-methyl-pyridin-3-yl)amine was prepared as described in Example 1 to yield after trituration with diethyl ether 51 mg (0.16 mmol, 73%) of the title hydrochloride as a yellow powder.

Sources & evidence

ORD record
ord-fd7704d67dec44ca92d8522657b231df
Source dataset
uspto-grants-2007_04
Patent number
US07205411B2

Reaction notes

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