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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1271579Generated: November 2, 2026

HCID 69053505, compound → HCID 57983260, compound

https://huagongshe.com/reaction/1271579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69053505HCID 69053505—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57983260HCID 5798326091.4%

Reaction Steps

A mixture of intermediate (7) (0.019 mol) in methanol (150 ml) was hydrogenated with palladium-on-carbon (10%, 2 g) as a catalyst. After uptake of hydrogen (1 equivalent), the catalyst was filtered off and the filtrate was evaporated, yielding 4 g of (trans)-4-(aminomethyl)-1-[2-(1,3-dioxolan-2-yl)ethyl]-3-piperidinol (intermediate 8).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07205410B2
Source datasetuspto-grants-2007_04
ORD IDord-5c1875c7329742df800694c3364d52a8
Source noteuspto-grants-2007_04