1-(Methylsulfonyl)spiro[indoline-3,4'-piperidine] hydrochloride → HCID 10113201, compound

HRID 1271619Notes

Reaction equation

HRID 1271619 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[NH:10][C:11](=[O:19])OC1C=CC=CC=1.Cl.[CH3:21][S:22]([N:25]1[C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[C:27]2([CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH2:26]1)(=[O:24])=[O:23]>>[CH2:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH2:1][CH:2]1[NH:10][C:11]([N:30]1[CH2:31][CH2:32][C:27]2([C:33]3[C:38](=[CH:37][CH:36]=[CH:35][CH:34]=3)[N:25]([S:22]([CH3:21])(=[O:23])=[O:24])[CH2:26]2)[CH2:28][CH2:29]1)=[O:19]

Participants

3

Reactant 2

HCID 219560841-(Methylsulfonyl)spiro[indoline-3,4'-piperidine] hydrochlorideHCID 22936230HCID 22936230, compound

Product 1

HCID 10113201HCID 10113201, compound

Procedure

Compounds of Examples 85 to 88 were obtained by following the same procedure as in Example 84, except that phenyl N-(2-indanyl)carbamate and 1-methanesulfonylspiro[indoline-3,4′-piperidine]hydrochloride used in Example 84 were replaced with the corresponding starting materials of each desired compound.

Sources & evidence

ORD record
ord-1611ee5af9a64698942df322d9d7ff0d
Source dataset
uspto-grants-2007_04
Patent number
US07205417B2

Reaction notes

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