HCID 69418848, compound → HCID 131726336, compound

Participants

Reaction Steps

The title compound was synthesized by substituting 2-(2-(S)-cyano-pyrrolidine-1-carbonyl)-5-(R/S)-(2-m-tolyl-vinyl)-pyrrolidine-1-carboxylic acid tert-butyl ester in Example 36 with 2-(2-(S)-cyano-pyrrolidine-1-carbonyl)-5-(R/S)-(2-p-chlorophenyl-vinyl)-pyrrolidine-1-carboxylic acid tert-butyl ester. 1H NMR (400 MHz, MeOH-d4) δ 1.83 (m, 1H), 1.98 (m, 2H), 2.24 (m, 6H), 2.71 (m, 4H), 3.64 (t, J=6.60 Hz, 2H), 3.73 (m, 1H), 4.59 (t, J=8.29 Hz, 1H), 7.25 (d, J=8.29 Hz, 2H), 7.31 (d, J=8.29 Hz, 2H) ppm. MS (ESI) m/z 332, 334 (M+H)+.

Provenance & Evidence