反应详情

温度

100 °C

A mixture of 21 g. phenol, 13 g. potassium hydroxide and 270 g. o-chlorotoluene was converted to a water-free slurry of potassium phenoxide by azeotropic distillation of all the water formed. After cooling back to 100° C., 28.8 g. of 1-chloro-8-nitroanthraquinone was charged and the whole heated and stirred at 130° C. for 6 hours. The product was isolated by steam distillation, filtration, washing and drying. A 37.7 g. yield (96.2% of theory) of a product identical to authentic 1,8-diphenoxyanthraquinone in a thin layer chromatogram and free of starting material was obtained.

1. additionA mixture of 21 g
2. distillationo-chlorotoluene was converted to a water-free slurry of potassium phenoxide by azeotropic distillation of all the water
3. customformed
4. temperaturethe whole heated
5. customThe product was isolated by steam distillation, filtration
6. washwashing
7. customdrying