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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1271681Generated: November 4, 2026

Nitric Acid → HCID 21873584, compound

https://huagongshe.com/reaction/1271681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
Reactant2-Fluoro-4-hydroxybenzonitrileHCID 2734675—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
SolventEthanolHCID 702—
ProductHCID 21873584HCID 21873584—

Reaction Steps

This was prepared by from 2-fluoro-4-hydroxy-benzonitrile by nitration (concentrated nitric acid in acetic acid at 40° C.) followed by hydrogenation in ethanol over 10% palladium/carbon.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07205408B2
Source datasetuspto-grants-2007_04
ORD IDord-bccfb429fbf64628b176e1b3f3dbb74b
Source noteuspto-grants-2007_04