Thionyl Chloride → HCID 18453171, compound

Participants

Reaction Steps

3-Chloro-1H-indole-6-carboxylic acid (200 mg) was mixed with 3 mL of SOCl2. The mixture was refluxed for 1 h and evaporated to dryness. Benzene (2 mL) was added and evaporated twice in order to eliminate residual SOCl2. The dark oil was triturated in ether/CH2Cl2 to yield 3-chloro-1H-indole-6-carbonyl chloride as a dark solid, which was used without further purification.

Provenance & Evidence