HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzenesulfonyl chloride → HCID 18455131, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 18455218 | HCID 18455218 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18455131 | HCID 18455131 | — |
Reaction Steps
4-chlorobenzenesulfonylchloride (0.26 mmol) was added to a methylene chloride (0.2 M) solution of triethylamine (1.0 mmol) and 3-{3-Methoxy-4-[2-(4-methyl-thiazol-5-yl)-ethoxy]-benzylamino)-azepan-2-one (7) (0.26 mmol), and stirred at room temperature for 12 h. The product (8) was obtained by purification upon reverse phase HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208488B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-72e7a96599f34a6e8efdaa8dc407e81c |
| Source note | uspto-grants-2007_04 |