HCID 10089559, compound → HCID 10408511, compound

HRID 1271849Notes

Reaction equation

HRID 1271849 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]([C:17]1[S:21][C:20]2[CH:22]=[CH:23][C:24]([O:26][CH2:27][CH2:28][N:29]3[CH2:34][CH2:33][O:32][CH2:31][CH2:30]3)=[CH:25][C:19]=2[CH:18]=1)=[O:16])(C)(C)C.NC1C=CC=CC=1NC(C1SC2C=CC(OCCN(C)C)=CC=2C=1)=O>>[NH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]([C:17]1[S:21][C:20]2[CH:22]=[CH:23][C:24]([O:26][CH2:27][CH2:28][N:29]3[CH2:30][CH2:31][O:32][CH2:33][CH2:34]3)=[CH:25][C:19]=2[CH:18]=1)=[O:16]

Participants

3

Reactant 2

HCID 10089559HCID 10089559, compoundHCID 69490140HCID 69490140, compound

Product 1

HCID 10408511HCID 10408511, compound

Procedure

was prepared from (2-{[5-(2-Morpholin-4-yl-ethoxy)-benzo[b]thiophene-2-carbonyl]-amino}-phenyl)-carbamic acid tert-butyl ester (11) in an analogous manner to that described for the preparation of (1) example 1, step 5; white solid, mp. 166–169° C.

Sources & evidence

ORD record
ord-143ad3471f6143f1bfcaba8015e487f9
Source dataset
uspto-grants-2007_04
Patent number
US07208491B2

Reaction notes

Loading…